Ostrow Professor Malcolm Snead is forging new pathways in bone repair — and it could impact all kinds of places in the body. Bone is crucial. After blood, it’s the most frequently transplanted tissue, with 1.6 to 2 million bone transplants performed in the United States each year. One of the most commonly performed […]
A new gel technology pioneered by Janet Moradian-Oldak and her team may eventually reach an elusive goal: filling without drilling. Around the globe, dental cavities are the leading source of disability and pain: they affect 35 percent of the world’s population, with an economic impact in the hundreds of billions of dollars. Still, the […]
Ostrow researcher Jianfu “Jeff” Chen has found a twist in the understanding of how Zika impacts the developing brain. The Zika virus has spread to 44 countries, with thousands infected and thousands of babies born with microcephaly, a rare complication that causes small heads. But even though research dollars are being poured into understanding the […]
Ostrow Professor and Associate Dean of Research Yang Chai’s research is heavily focused on cleft lip and cleft palate and how stem cell therapy might be used to detect — and even prevent — cleft formation. Every time we drink or breathe, the soft palate is hard at work. It acts like a trap door, […]
With help from the National Institutes of Health grant, the associate professor and his team aim to get FDA approval and bring the drug to market. Above: Illustration by Carl Wiens/i2iartOstrow Associate Professor Parish Sedghizadeh DDS ’01 and his team have been awarded a $1.5-million grant from the National Institutes of Health to continue research […]
Mutation in IFT88 causes birth defects in mouse models; the same gene affects human face and skull development, though more research is needed A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect. The gene intraflagellar transport 88 (IFT88) ensures […]
Parish Sedghizadeh’s study is featured on cover of March 23 issue of the Journal of Medicinal Chemistry It is one of the strongest materials in the human body, yet bone is surprisingly vulnerable when it comes to bacterial infections. In fact, patients who have developed an infection in any of their 206 bones can often face dire […]
An Ostrow-initiated research team called C-DOCTOR (Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration) is one step closer to developing products that facilitate tissue regeneration, thanks to a $12-million award from the National Institute of Dental and Craniofacial Research (NIDCR). The financial reward stems from a challenge issued by NIDCR two years ago […]
Jian Xu investigates the way that cells perish or thrive — and it may lead to new ways to fight cancer and heal damaged hearts. Basic science can often be far from basic — especially for Jian Xu, who believes cells are kind of like people. “In simple terms, we look at how cells determine […]
Yang Chai PhD ’91 DDS ’96 and colleagues from Keck School of Medicine of USC to use funds to investigate stem cell treatment for syndrome that causes children’s skull bones to fuse prematurely. It might surprise you to learn that your cranium is not one continuous smooth bone encasing your brain. It’s actually comprised […]
