Dental enamel is tricky stuff. Even though it’s the body’s hardest material, if it wears away from cavities, acidic food or drinks or overbrushing, it doesn’t regenerate. All that could change in the future, though. Ostrow Professor Janet Moradian-Oldak has been developing a special hydrogel that can promote the growth of an enamel-like surface […]
Findings published in Biomaterials Special Issue of the Journal of the Minerals, Metals and Materials Society. Three million people in the United States currently have dental implants, and every year that number increases by about 500,000. But, for some, getting a dental implant is not the end of the story. Similar to what occurs with […]
Yang Chai PhD ’91, DDS ’96 shares his discovery in recent study published in the journal Bone Research. Could we be one step closer to developing a biological treatment for craniosynostosis? Building upon a body of research that demonstrated that the premature fusion of skull bones — which can cause a host of problems […]
NAM membership is considered one of the highest honors in the health and medicine field. Ostrow Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been elected to the National Academy of Medicine (NAM), a membership which is considered one of the highest honors in the fields of health and medicine. “Your […]
Ostrow Professor Malcolm Snead is forging new pathways in bone repair — and it could impact all kinds of places in the body. Bone is crucial. After blood, it’s the most frequently transplanted tissue, with 1.6 to 2 million bone transplants performed in the United States each year. One of the most commonly performed […]
A new gel technology pioneered by Janet Moradian-Oldak and her team may eventually reach an elusive goal: filling without drilling. Around the globe, dental cavities are the leading source of disability and pain: they affect 35 percent of the world’s population, with an economic impact in the hundreds of billions of dollars. Still, the […]
Ostrow researcher Jianfu “Jeff” Chen has found a twist in the understanding of how Zika impacts the developing brain. The Zika virus has spread to 44 countries, with thousands infected and thousands of babies born with microcephaly, a rare complication that causes small heads. But even though research dollars are being poured into understanding the […]
Ostrow Professor and Associate Dean of Research Yang Chai’s research is heavily focused on cleft lip and cleft palate and how stem cell therapy might be used to detect — and even prevent — cleft formation. Every time we drink or breathe, the soft palate is hard at work. It acts like a trap door, […]
With help from the National Institutes of Health grant, the associate professor and his team aim to get FDA approval and bring the drug to market. Above: Illustration by Carl Wiens/i2iartOstrow Associate Professor Parish Sedghizadeh DDS ’01 and his team have been awarded a $1.5-million grant from the National Institutes of Health to continue research […]
Mutation in IFT88 causes birth defects in mouse models; the same gene affects human face and skull development, though more research is needed A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect. The gene intraflagellar transport 88 (IFT88) ensures […]